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Case Reports
[A case report. Rosiglitazone treatment was highly effective yet had to be terminated].
- Martin Ridderstråle and Leif Groop.
- Endokrinologiska kliniken, Universitetssjukhuset MAS, Malmö. martin.ridderstrale@endo.mas.lu.se
- Lakartidningen. 2002 Jan 31; 99 (5): 407-10.
AbstractThe thiazolidinediones were introduced as oral hypoglycemic drugs in Sweden during the fall of 2000. A case is reported in which a woman with insulin-dependent type-2 diabetes and both macro- and microangiopathy and pronounced insulin resistance was treated with rosiglitazone (Avandia). Within three months insulin doses could be reduced by 36% (from 176 to 112 units insulin daily) and concomitantly Ery-HbA1c was reduced from 8.4 to 5.3%. In spite of this dramatic effect on glucose homeostasis administration of the drug had to be discontinued due to critical congestive heart failure.
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