• Blood Coagul. Fibrinolysis · Jan 2013

    Case Reports

    Effectiveness of low-dose prolonged infusion of tissue plasminogen activator in a nonagenarian patient with acute pulmonary embolism and main pulmonary artery thrombus.

    • Mustafa Yildiz, Suleyman Karakoyun, Rezzan Deniz Acar, and Mehmet Ozkan.
    • Department of Cardiology, Kartal Koşuyolu Yüksek Ihtisas Educational and Research Hospital, Istanbul, Turkey. mustafayilldiz@yahoo.com
    • Blood Coagul. Fibrinolysis. 2013 Jan 1; 24 (1): 95-6.

    AbstractAcute pulmonary embolism is an important emergency disease which frequently results in life-threatening complication. Systemic fibrinolysis is recommended as standard, first-line therapy in patients with massive pulmonary embolism. In the case described in this report, a 95-year-old woman was treated with low-dose prolonged infusion of tissue plasminogen activator for acute pulmonary embolism and mobile thrombus in the main pulmonary artery and right pulmonary artery. On the basis of echocardiographic findings, acute thrombolysis with low-dose prolonged infusion of tissue plasminogen activator was performed resulting in hemodynamic stabilization of the patient and complete resolution of the pulmonary artery thrombus.

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