• Anesteziol Reanimatol · Mar 2012

    [Effect of intraoperative infusion-transfusion therapy on mortality of patients with massive blood loss].

    • V V Valetova, A S Ermolov, V Kh Timerbaev, and A V Dragunov.
    • Anesteziol Reanimatol. 2012 Mar 1 (2): 23-7.

    AbstractThe aim of the research is to determine the influence of infusion-transfusion therapy of the volume and structure on intraoperation and hospital lethality in patients with injuries and diseases, complicated in blood loss, exceeding circulating blood volume (CBV). It was conducted a retrospective analysis of the anaesthesia flow, infusion-transfusion therapy and treatment results in 112 patients with injuries and diseases complicated in intra-abdominal bleeding, volume of more than 4 liters. It was found that the risk of death increases in low-volume infusion therapy (less than 1.5 volume of blood), use of the maximum permitted doses of colloids, high speed of infusion therapy. Adverse factors of intraoperative transfusion: the lack of intraoperative compensation erythrocytes(less than 50% of the lost), ones transfuse more than 2 standard doses of the donor's erythrocytes and large volumes of fresh frozen plasma (FFP).

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