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J Gynecol Obstet Biol Reprod (Paris) · Apr 2011
Comparative Study[Comparison between two analgesic protocols on IVF success rates].
- O Mialon, J Delotte, P Lehert, M Donzeau, M Drici, V Isnard, and A Bongain.
- Service de gynécologie-obstétrique-reproduction et de médecine fœtale, hôpital de l'Archet, CHU de Nice, 2, route Saint-Antoine-de-Ginestière, 06200 Nice, France. omialon@free.fr
- J Gynecol Obstet Biol Reprod (Paris). 2011 Apr 1; 40 (2): 137-43.
ObjectivesAnalgesic protocols administered before a follicular puncture under local anesthesia are well tolerated when using NSAIDs, but we still do not know their possible impacts on in vitro fertilization (IVF) outcomes.Material And MethodsA retrospective monocentric study using two consecutive temporal cohorts of patients was conducted to compare two analgesic protocols: paracetamol/alprazolam (P/A), then nefopam/ketoprofen (N/K).ResultsWe demonstrated that biochemical pregnancy rate and the others outcomes of IVF are not significantly influenced by the type of analgesic protocol used.ConclusionThe protocol N/K enhances patient comfort without jeopardizing the IVF success rates.Copyright © 2010 Elsevier Masson SAS. All rights reserved.
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