• J. Occup. Environ. Med. · Sep 2011

    Sarcoidosis diagnosed after September 11, 2001, among adults exposed to the World Trade Center disaster.

    • Hannah T Jordan, Steven D Stellman, David Prezant, Alvin Teirstein, Sukhminder S Osahan, and James E Cone.
    • World Trade Center Health Registry, New York City Department of Healthand Mental Hygiene, 42-09 28th St, 7th floor, Long Island City, NY 11101, USA. hjordan1@health.nyc.gov
    • J. Occup. Environ. Med. 2011 Sep 1; 53 (9): 966-74.

    ObjectiveExplore relationships between World Trade Center (WTC) exposures and sarcoidosis.MethodsSarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among WTC Health Registry enrollees. Cases diagnosed after Registry enrollment were included in a nested case-control study. Controls were matched to cases on age, sex, race or ethnicity, and eligibility group (eg, rescue or recovery worker).ResultsWe identified 43 cases of post-9/11 sarcoidosis. Twenty-eight incident cases and 109 controls were included in the case-control analysis. Working on the WTC debris pile was associated with sarcoidosis (odds ratio 9.1, 95% confidence interval 1.1 to 74.0), but WTC dust cloud exposure was not (odds ratio 1.0, 95% confidence interval 0.4 to 2.8).ConclusionsWorking on the WTC debris pile was associated with an elevated risk of post-9/11 sarcoidosis. Occupationally exposed workers may be at increased risk.(C)2011The American College of Occupational and Environmental Medicine

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