-
Can. J. Physiol. Pharmacol. · Dec 2007
Biography Historical ArticleAdventures in drug disposition: pas seulement pâté de foie.
- Daniel S Sitar.
- Department of Pharmacology and Therapeutics, Faculty of Medicine, Centre on Aging, University of Manitoba, A220-753 McDermot Avenue, Winnipeg, MB R3E 0T6, Canada. sitar@cc.umanitoba.ca
- Can. J. Physiol. Pharmacol. 2007 Dec 1; 85 (12): 1215-25.
AbstractInterindividual variability in drug disposition and effect has served to confound the optimization of drug therapy. Over my career, I have focused on delineating mechanisms that contribute to this variability, with the goal of improving the benefit : risk ratio when drug therapy is chosen as an intervention strategy. In this manuscript, I present some of our experimental findings that I believe have contributed to an increased understanding of variability in drug disposition and efficacy.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..