• Int J Artif Organs · Oct 1999

    Case Reports

    Saline-induced dilutional acidosis in a maintenance hemodialysis patient.

    • B I Mirza, M Sahani, D J Leehey, S B Patel, V L Yang, and T S Ing.
    • Department of Medicine, Veterans Affairs Hospital, Hines, Illinois 60141, USA.
    • Int J Artif Organs. 1999 Oct 1; 22 (10): 676-8.

    AbstractA patient with end-stage renal disease developed severe hyperchloremic acidosis (venous serum total CO2 level of 10 mmol/L) after treatment with 16 L of isotonic saline. Analysis of this case and published literature indicates that dilutional acidosis may result when very large volumes of isotonic saline are administered intravenously, especially in patients with impaired or absent renal function.

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