• Europace · Mar 2009

    Case Reports

    Long-QT syndrome and torsades de pointes in a patient with Takotsubo cardiomyopathy: an unusual case.

    • Saagar Mahida, Chrysoula Dalageorgou, and Elijah R Behr.
    • Department of Cardiology, St George's Hospital, Blackshaw Road, London, UK. saagar7m7@yahoo.co.uk
    • Europace. 2009 Mar 1; 11 (3): 376-8.

    AbstractTakotsubo cardiomyopathy is a syndrome characterized by transient left ventricular apical ballooning associated with electrocardiogram (ECG) changes and minimal myocardial enzymatic release, mimicking acute myocardial infarction in patients without significant coronary disease at angiography. We report an unusual case of a patient who presented with Takotsubo cardiomyopathy associated with long-QT syndrome and who developed cardiac arrest secondary to torsades de pointes.The relationship between Takotsubo cardiomyopathy and abnormal repolarization has been well documented. Despite this, there have been few reports of malignant ventricular arrhythmias or sudden death. This report suggests that prolongation of QTc interval in Takotsubo cardiomyopathy may not be as benign as previously suggested but may in fact uncover an abnormality of repolarization that may be genetic in basis and carry a risk of sudden death.

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