• J Chin Med Assoc · Oct 2010

    Case Reports

    Antivenin-related serum sickness.

    • Chin-Yuan Huang, Dong-Zong Hung, and Wei-Kung Chen.
    • Emergency Department, China Medical University, Taichung, Taiwan, R.O.C.
    • J Chin Med Assoc. 2010 Oct 1; 73 (10): 540-2.

    AbstractSerum sickness is a type III hypersensitivity reaction that occurs due to the deposition of excessive circulating immune complexes in patients treated with foreign proteins or haptens. Serum sickness induced by antivenin for snakebites has been frequently reported in the USA, but not in Taiwan. This difference may be due to the efficacy and dosage of antivenins administered to treat snakebites in Taiwan. We report a case presenting with serum sickness after receiving a total of 20 vials of polyvalent antivenin therapy for the treatment of snakebite. A 59-year-old male suffered from fever, headaches, polyarthritis, and diffused skin rash approximately 10 days after administration of the antivenin. The large dose of antivenin administered in this case might have been the cause of the development of serum sickness. Physicians should be aware of the potential for serum sickness in cases of large-dose antivenin use.Copyright © 2010 Elsevier. Published by Elsevier B.V. All rights reserved.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…