• James P Curtain, Prasanna Sankaran, Ajay V Kamath, and Phyo K Myint.
• Addenbrooke's University Hospital, Cambridge, Cambridgeshire CB2 0QQ, UK ; School of Medicine & Dentistry, Division of Applied Health Sciences, C/o Room 4013, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK.
• Biomed Res Int. 2013 Jan 1; 2013: 590407.

Background And ObjectivesThe study aims to assess the usefulness of age-independent criteria CURSI and temperature adjusted CURSI (CURASI) compared to CURB-65 in predicting community-acquired pneumonia (CAP) mortality. The criteria, CRSI and CRASI, were adapted for use in primary care and compared to CRB-65.MethodsA retrospective analysis of a prospectively identified cohort of community-acquired pneumonia inpatients was conducted. Outcomes were (1) mortality and (2) mortality and/or ICU admission within six weeks.Results95 patients (median age = 61 years) were included. All three criteria had similar sensitivity in predicting mortality alone, with CURB-65 having slightly higher specificity. When predicting mortality and/or intensive care admission, CURSI/CURASI showed higher sensitivity and slightly lower specificity. CRSI and CRASI had higher sensitivity and lower specificity when compared with CRB-65 for predicting both primary and secondary outcomes. Results for both analyses had P values >0.05.ConclusionsIn a cohort of younger patients CURSI and adjusted CURSI perform at least as well as CURB-65, with a similar trend for CRSI and adjusted CRSI compared to CRB-65. Further studies are needed in different age groups and in primary and secondary care settings.

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