• Yu-Hung Lin, Jiann-Loung Hwang, Lee-Wen Huang, and Heng-Ju Chen.
• Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital Taipei 777, Taiwan.
• J Minim Invasive Gynecol. 2005 Jul 1; 12 (4): 347-50.

Study ObjectiveTo assess the efficacy of sublingual buprenorphine in the relief of pain associated with office hysteroscopy.DesignProspective, randomized study (Canadian Task Force classification I).SettingTertiary medical center.PatientsOne hundred sixty-four women referred for office hysteroscopy from September 2003 through March 2004.InterventionBefore hysteroscopy, 80 women received a tablet of buprenorphine (group A), and 84 women received a placebo (group B). Their pain sensations were evaluated on a 10-cm visual analog scale, and they were asked about the adverse reactions and level of satisfaction on the following day.Measurements And Main ResultsThe pain score in group A was 3.3 +/- 1.1, which was similar to 3.2 +/- 1.3 in group B. The pain scores in subgroups of women also were similar within the same group and between the two groups. Thirty-one women (38.8%) in group A reported adverse reactions, including nausea, vomiting, and drowsiness, while none in group B reported any adverse reactions.ConclusionOffice hysteroscopy with a 3.1-mm flexible hysteroscope is a well-tolerated procedure. Sublingual buprenorphine is not helpful in relieving the pain associated with hysteroscopy but is associated with significant adverse reactions.

24 keywords...

hide…