• Lin Xu, Yong-Gui Ge, Jia-Mei Liu, Hong-Shi Wang, Li-Ping Yu, Zhu-Hua Ni, and Liang Cui.
• Heart Center, Beijing Chaoyang Hospital, the Capital Medical University, Beijing, China. xul2301@sina.com.cn
• Zhonghua Nei Ke Za Zhi. 2008 Jun 1; 47 (6): 472-4.

ObjectiveTo observe the effect of reperfusion therapy on the prognosis of acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) in reperfusion era.Methods89 cases of AMI with CS were included with 57 male and 32 female. 50 cases received conservative therapy and 39 cases reperfusion therapy. 28 of the 39 cases had successful reperfusion and 11 cases failed. 18 patients had intra-aortic balloon pump (IABP) within 1 hour of CS, they constituted an early group; 35 patients treated with IABP 1 hour after CS were of a late group. A group of 36 cases were not treated with IABP (no IABP group).ResultsThe mortality of the early group with IABP was significantly lower than that of the late and no IABP group (33.3% vs. 74.2% vs. 86.1%, P < 0.01). The mortality of the group with successful reperfusion was significantly lower than that of unsuccessful reperfusion and conservative no IABP group (42.8% vs. 81.8% vs. 84.0% , P < 0.01). logistic regression analysis showed that successful reperfusion therapy (OR 4.232, 95% CI 1. 07 - 12.730, P = 0.01) and THE TIME of using IABP (OR 0.22, 95% CI 0.063 - 0.764, P =0.017) were independent risk factors for death.ConclusionEarly successful reperfusion and early institution of IABP were the most important therapeutic measures for reducing mortality of AMI complicated by CS.

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