• Human pathology · Sep 2014

    Case Reports

    Severe enterocolitis associated with antiepileptic-induced drug reaction with eosinophilia and systemic symptoms.

    • Eric A Swanson, Lawrence Low, and Bita V Naini.
    • Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095.
    • Hum. Pathol. 2014 Sep 1; 45 (9): 1973-7.

    AbstractDrug reaction with eosinophilia and systemic symptoms (DRESS) is a rare but serious drug-induced reaction with cutaneous, hematologic, and solid-organ injury. Antiepileptic drugs are one of the most common classes of drugs implicated in DRESS. A high morbidity and mortality may result, especially if the offending drug is not withdrawn promptly. Although DRESS may involve many organs, severe involvement of the gastrointestinal tract in DRESS and/or in association with antiepileptic drugs has rarely been reported. We report detailed clinical and histopathologic findings of a fatal case of DRESS syndrome resulting from antiepileptic drug treatment that was accompanied by severe enterocolitis, malabsorption, and cachexia.Copyright © 2014 Elsevier Inc. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…