• Ines Kapferer, Claudia Pflug, Irene Kisielewsky, Johannes Giesinger, Ulrike S Beier, and Herbert Dumfahrt.
• Department of Restorative and Operative Dentistry, Dental School, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria. ines.kapferer@gmx.net
• Acta Odontol. Scand. 2013 May 1; 71 (3-4): 994-9.

ObjectiveThe aim of this study was to evaluate the clinical efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate relative to calcium carbonate alone in the reduction of dentin hypersensitivity in a randomized, double-blind, split-mouth clinical trial.Materials And MethodsSixty teeth (30 subjects) with an air blast hypersensitivity score of 2 or 3 (Schiff Cold Air Sensitivity Scale) were randomly assigned to one of two treatment groups: (1) test paste containing 8% arginine and calcium carbonate (elmex sensitive professional desensitizing paste) and (2) control paste: paris white (calcium carbonate). Tactile and air blast dentin hypersensitivity examinations were performed at baseline, immediately after paste application and 4 and 12 weeks later.ResultsA statistically significant difference in air blast (p = 0.001) and tactile (p = 0.047) hypersensitivity reduction over time was observed between the two therapy modes. After 12-weeks, statistically significant differences were indicated between the test and control group with respect to baseline-adjusted mean tactile (41.94%; p = 0.038) and air blast hypersensitivity scores (46.5%; p = 0.017).ConclusionsThe tested in-office desensitizing paste containing 8.0% arginine and calcium carbonate provides significantly greater hypersensitivity relief compared to calcium carbonate alone.

19 keywords...

hide…