• Skeletal radiology · Oct 1996

    Case Reports

    Diaphyseal telangiectatic osteosarcoma as a second tumor after bilateral retinoblastomas.

    • M J Brown, P M Logan, J X O'Connell, D L Janzen, and D G Connell.
    • Department of Radiology, University of British Columbia, Vancouver, Canada.
    • Skeletal Radiol. 1996 Oct 1; 25 (7): 685-8.

    AbstractIn this report, we describe the clinical, imaging, and pathologic findings in a case of diaphyseal telangiectatic osteosarcoma arising 23 years after successful treatment of bilateral retinoblastomas. To our knowledge, telangiectatic osteosarcoma occurring as a second tumor in this setting, outside the radiation treatment field, has not been previously reported. The association of the RB-1 gene defect with retinoblastomas and other tumors is discussed. Also, the computed tomography and magnetic resonance imaging findings in telangiectatic osteosarcoma are described and discussed.

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