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Case Reports
Diaphyseal telangiectatic osteosarcoma as a second tumor after bilateral retinoblastomas.
- M J Brown, P M Logan, J X O'Connell, D L Janzen, and D G Connell.
- Department of Radiology, University of British Columbia, Vancouver, Canada.
- Skeletal Radiol. 1996 Oct 1; 25 (7): 685-8.
AbstractIn this report, we describe the clinical, imaging, and pathologic findings in a case of diaphyseal telangiectatic osteosarcoma arising 23 years after successful treatment of bilateral retinoblastomas. To our knowledge, telangiectatic osteosarcoma occurring as a second tumor in this setting, outside the radiation treatment field, has not been previously reported. The association of the RB-1 gene defect with retinoblastomas and other tumors is discussed. Also, the computed tomography and magnetic resonance imaging findings in telangiectatic osteosarcoma are described and discussed.
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