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Pediatr. Infect. Dis. J. · May 2009
Case ReportsDaptomycin therapy failure in an adolescent with methicillin-resistant Staphylococcus aureus bacteremia.
- Lara M Jacobson, Aaron M Milstone, Jonathan Zenilman, Karen C Carroll, and Ravit Arav-Boger.
- Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA. ljacob19@jhmi.edu
- Pediatr. Infect. Dis. J. 2009 May 1; 28 (5): 445-7.
AbstractDaptomycin is a Food and Drug Administration-approved alternative to vancomycin for the treatment of serious methicillin-resistant Staphylococcus aureus infections in adults. Treatment failure with daptomycin is increasingly reported in adults, but data in children are limited. We report an adolescent patient with severe burn injuries who had persistent methicillin-resistant Staphylococcus aureus bacteremia and rapidly developed nonsusceptibility to daptomycin. We review the relevant literature.
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