• Ann Med Interne (Paris) · Jun 2001

    Case Reports

    [Rapidly progressive dementia disclosing primary angiitis of the central nervous system].

    • G Castelnovo, S Bouly, M Vladut, C Marty-Double, and P Labauge.
    • Service de Neurologie, CHU de Montpellier-Nimes, 2, avenue du Pr. Debre, 30029 Nimes Cedex, France.
    • Ann Med Interne (Paris). 2001 Jun 1; 152 (4): 273-5.

    AbstractAngiitis of the central nervous system involves a wide spectrum of clinical symptoms. Complementary exams (CSF, neuroradiological exams) are not very specific and sensitive. Diagnostic procedures often require cortical and leptomeningeal biopsy. Treatment, based on corticosteroids and cyclophosphamid, have greatly improved prognosis. We report a rapidly progress dementia syndrome that revealed angiitis of the central nervous system. Corticosteroid treatment did not prevent a fatal outcome. Autopsy findings confirmed the diagnosis of central nervous leucocytoclastic angiitis.

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