• J Pain Symptom Manage · Sep 2016

    Symptom Burden and End-of-Life Treatment Preferences in the Very Old.

    • Steven M Albert, June R Lunney, Lei Ye, Robert Boudreau, Diane Ives, Suzanne Satterfield, Hilsa N Ayonayon, Susan M Rubin, Anne B Newman, Tamara Harris, and Health ABC Study.
    • Department of Behavioral and Community Health Sciences, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. Electronic address: smalbert@pitt.edu.
    • J Pain Symptom Manage. 2016 Sep 1; 52 (3): 404-11.

    ContextEnd-of-life (EOL) treatment preferences among the very old (age 85+) may differ from preferences in younger aged populations because of high levels of symptom burden and disability and high risk of mortality. It is unclear if symptom burden or level of disability is more important for such preferences.ObjectivesTo investigate whether distress from daily symptom burden was an independent correlate of EOL treatment preferences over two years of follow-up in people with median age 86 (participants) and 88 (reported by proxies) at baseline.MethodsThe End of Life in Very Old Age is an ancillary study to the Health, Aging and Body Composition study. At baseline in Year 15 of Health, Aging and Body Composition, 1038 participants and 189 proxies reported levels of symptom distress every quarter, as well as 0-8 EOL treatment preferences elicited once each year.ResultsAt baseline, the mean (SD) count of EOL treatment preferences was 4.2 (2.1) in participants, and 2.9 (2.3) in proxies. EOL treatment preference was not associated with symptom distress. By contrast, black race, male gender, and reported ease walking a quarter mile were independently associated with more aggressive EOL treatment preferences.ConclusionPreferences for more aggressive EOL treatment were not related to daily symptom distress but were significantly more likely to be endorsed among those with better mobility, suggesting that disability is an independent predictor of EOL treatment preferences in the very old.Copyright © 2016 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

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