• Int Orthop · Apr 2013

    Multicenter Study

    Smoking is a risk factor of organ/space surgical site infection in orthopaedic surgery with implant materials.

    • François Durand, Philippe Berthelot, Celine Cazorla, Frederic Farizon, and Frederic Lucht.
    • Department of Infectious Diseases, University Hospital and University Jean Monnet, Saint-Etienne, France.
    • Int Orthop. 2013 Apr 1; 37 (4): 723-7.

    PurposeIn recent guidelines, smoking is reported as a factor increasing the risk of surgical site infection (SSI). The accurate analysis of the literature shows that this recommendation relies on low level of evidence in orthopaedic surgery with material implantation (arthroplasty components or implants for internal fixation). This study aimed to assess the attributable risk of smoking on organ/space SSI in orthopaedic surgery with implants.MethodsRisk factors of organ/space SSI were studied in a prospective cohort including 3,908 patients from June 2003 to December 2006.ResultsSmoking was found as a significant risk factor for organ/space SSI. We also observed a significant difference between smokers and non-smokers for surgical wound complications (hematoma, discharge or wound dehiscence) during the period between surgical procedure and discharge from hospital.ConclusionThis is the first large prospective report of a significant association between smoking and organ/space SSI in orthopaedic surgery with implants.

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