• Arch. Gynecol. Obstet. · May 2011

    Randomized Controlled Trial

    Umbilical cord blood acid-base and gas analysis after early versus delayed cord clamping in neonates at term.

    • Catalina De Paco, Jesús Florido, Mari Carmen Garrido, Sonia Prados, and Luis Navarrete.
    • Servicio de Obstetricia y Ginecología, Hospital Universitario Virgen de Arrixaca, Carretera Madrid-Cartagena, s/n El Palmar, Murcia, Spain. katy.depaco@gmail.com
    • Arch. Gynecol. Obstet. 2011 May 1; 283 (5): 1011-4.

    ObjectiveTo compare umbilical cord acid-base status and blood gas analysis between umbilical cords clamped within 10 s and at 2 min of delivery.MethodsA total of 158 healthy full-term mothers were randomly assigned to an early clamping (<10 s post-delivery, n = 79) or delayed clamping (2 min post-delivery, n = 79) group. After application of inclusion criteria, umbilical vein blood acid-base status and gases were analyzed in 65 early clamped and 51 delayed clamped cords. Fewer cases could be examined in the umbilical artery: 55 cords in the early clamping group and 44 in the delayed one.ResultsAcid-base and gas analysis results did not significantly differ between the groups in the umbilical vein or umbilical artery, with the exception of a higher (p < 0.001) mean umbilical artery pO(2) value in the delayed versus early clamping group. No significant differences in umbilical vein or artery pCO(2) or HCO(3) (-) values were observed between the early and delayed clamp groups.ConclusionsA delay of 2 min before umbilical cord clamping does not significantly change acid-base and gas analysis results, with the exception of a higher mean umbilical artery pO(2) value in the delayed clamping group.

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