• Laryngo- rhino- otologie · Nov 2006

    Case Reports

    [Therapy of postoperative nausea and vomiting in ENT--tardive dyskinesia as an adverse effect of metoclopramid--a case report].

    • S Tesche, C Henckell, and F U Metternich.
    • Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde des Universitätsklinikums Hamburg-Eppendorf. stesche@t-online.de
    • Laryngorhinootologie. 2006 Nov 1; 85 (11): 824-6.

    BackgroundPostoperative nausea and vomiting (PONV) are among the most common complications in operative medicine. Especially patients undergoing middle ear surgery or stapedectomy are frequently suffering from PONV. On the other hand vertigo might be a symptom of an operative complication. For symptomatic therapy a various number of different drugs is available.PatientWe describe the clinical course of a 25-years-old female patient, who presented with massive orofacial tardive dsykinesia after therapy with metoclopramide (MCP). She had stapedectomy in general anaesthesia and suffered from PONV. The dyskinesia was treated successfully with Biperiden 5 mg i. v.DiscussionTardive dyskinesia is a potential and in rare cases irreversible complication of MCP-therapy. The efficiacy of MCP is in controversy. Studies with 5-HT3-antagonists like Ondansetron or neuroleptics like Droperidol show good results in PONV especially after middle ear surgery.ConclusionTardive dyskinesia is a rare but possible drug-related adverse effect of MCP. After review of the literature we can not recommend MCP as an antiemetic drug in PONV.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…