-
Eur. J. Clin. Microbiol. Infect. Dis. · Oct 2001
Case ReportsDiagnosis of disseminated zygomycosis using a polymerase chain reaction assay.
- V Rickerts, J Loeffler, A Böhme, H Einsele, and G Just-Nübling.
- Klinikum der J.W. Goethe Universität, Medizinische Klinik III/Infektiologie, Frankfurt. Rickerts@em.uni-frankfurt.de
- Eur. J. Clin. Microbiol. Infect. Dis. 2001 Oct 1; 20 (10): 744-5.
AbstractInvasive pulmonary zygomycosis is an uncommon opportunistic infection in patients with haematological malignancies. Clinical manifestations are in distinguishable from the more frequent invasive aspergillosis. Standard diagnostic methods like culture and microscopy from respiratory secretions have a low diagnostic sensitivity. A case in which proven invasive pulmonary zygomycosis was confirmed using a panfungal polymerase chain reaction assay in blood is presented. Since zygomycosis requires more aggressive treatment than aspergillosis (high-dose amphotericin B and surgical intervention), the polymerase chain reaction assay may improve the outcome of these often fatal infections by guiding the therapeutic approach through an early, non-invasive diagnosis.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..