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Obstetrics and gynecology · Feb 2011
Case ReportsHyperlipidemia-associated pancreatitis in pregnancy managed with fenofibrate.
- Amy E Whitten, Robert P Lorenz, and Joann M Smith.
- Department of Obstetrics and Gynecology, William Beaumont Hospital, Royal Oak, Michigan, USA. aewhitten@gmail.com
- Obstet Gynecol. 2011 Feb 1; 117 (2 Pt 2): 517-9.
BackgroundPancreatitis is a concerning clinical event during pregnancy, with high morbidity and mortality rates for mother and fetus. Hypertriglyceridemia is considered a rare cause of pancreatitis in pregnancy, with the majority of reported cases being associated with the lipid metabolism disorders.CaseWe report on a case of hypertriglyceridemia-induced pancreatitis in a woman presenting at 32 weeks of gestational age. Her dyslipidemia was not controlled with diet alone, necessitating medical intervention. Fenofibrate was used successfully. Recurrence of pancreatitis during the pregnancy was avoided, and a healthy neonate was delivered at 35 weeks of gestation.ConclusionFenofibrate was used safely and successfully during pregnancy in this case of hypertriglyceridemia-associated pancreatitis refractory to conservative measures.
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