• David De Bels, Philippe Gottignies, Marijke Reynders, Sébastien Roques, Stephan Wilmin, Véronique-Yvette Miendje Deyi, Sophie Jamart, and Jacques Devriendt.
• Intensive Care Department, Brugmann University Hospital, 4 Place Van Gehuchten, 1020, Brussels, Belgium. david.debels@chu-brugmann.be.
• J Med Case Rep. 2012 Jan 1; 6: 20.

IntroductionChlamydophila pneumoniae is a respiratory pathogen known to infect the upper and lower respiratory tracts. Infection severity can range from sub-clinical pulmonary infection to acute respiratory distress syndrome.Case PresentationA previously healthy 62-year-old Caucasian man was admitted to our hospital for acute respiratory failure. Serum samples obtained every week starting from the day of admission showed clear-cut seroconversion for C. pneumoniae antibodies. All other cultures obtained during the first days of hospitalization were negative. Despite maximal ventilatory support (high positive end expiratory pressure, fraction of inspired oxygen of 1.0, nitric oxide inhalation, neuromuscular blocking agents and prone positioning), our patient remained severely hypoxemic, which led us to initiate an extracorporeal membrane oxygenation treatment. Extracorporeal membrane oxygenation and hemodiafiltration were withdrawn on day 12. Our patient was extubated on day 18 and discharged from our Intensive Care Unit on day 20. He went home a month later.ConclusionWe describe the first published case of acute respiratory distress syndrome due to C. pneumoniae infection successfully treated by extracorporeal membrane oxygenation, a very useful tool in this syndrome. A quick and specific method for the definite diagnosis of Chlamydophila infection should be developed.

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