• Crit Care · Jan 2015

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    Is critical care ready for an economic surrogate endpoint?

    • M Elizabeth Wilcox and Gordon D Rubenfeld.
    • Department of Medicine, University Health Network, Toronto Western Hospital, 399 Bathurst Street, Room 411M 2nd Floor McLaughlin Wing, Toronto, ON, M5T 2S8, Canada. elizabeth.wilcox@utoronto.ca.
    • Crit Care. 2015 Jan 1;19:248.

    AbstractIntensive care is expensive, and thus a body of research has focused on strategies to reduce its costs. However, efforts to reduce the total cost of intensive care have met with limited success, partly because of the challenges of calculating how much a day in the ICU actually costs. We discuss these challenges and introduce the concept of total cost savings as an outcome of critical care trials, assuming statistically negative effects on mortality and quality of life.

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