• Acta Pharmacol. Sin. · Jun 2011

    Review

    Maternal-fetal fluid balance and aquaporins: from molecule to physiology.

    • Xiao-yan Sha, Zheng-fang Xiong, Hui-shu Liu, Xiao-dan Di, and Tong-hui Ma.
    • Department of Obstetrics, Guangzhou Women and Children's Medical Centre, Guangzhou Medical College, Guangzhou 510623, China.
    • Acta Pharmacol. Sin. 2011 Jun 1; 32 (6): 716-20.

    AbstractMaternal-fetal fluid balance is critical during pregnancy, and amniotic fluid is essential for fetal growth and development. The placenta plays a key role in a successful pregnancy as the interface between the mother and her fetus. Aquaporins (AQPs) form specific water channels that allow the rapid transcellular movement of water in response to osmotic/hydrostatic pressure gradients. AQPs expression in the placenta and fetal membranes may play important roles in the maternal-fetal fluid balance.

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