• Tanya Mailhot, Sylvie Cossette, Jean Lambert, Alexis Cournoyer, and André Y Denault.
• Montreal Heart Institute Research Center S-2490, Montreal, Quebec, Canada H1T 1C8; Faculty of Nursing, Universite de Montreal, Montreal, Quebec, Canada H3T 1A8. Electronic address: t.mailhot@umontreal.ca.
• J Crit Care. 2016 Aug 1; 34: 17-23.

PurposeA promising monitoring strategy for delirium is the use of cerebral oximetry, but its validity during delirium is unknown. We assessed the relationship between oximetry and delirium. We hypothesized that as cerebral oximetry values increased, delirium would resorb.Materials And MethodsAn observational study was conducted with 30 consecutive adults with delirium after cardiac surgery. Oximetry, delirium assessments, and clinical data were collected for 3 consecutive days after delirium onset. Oximetry was obtained using near-infrared spectroscopy. Delirium was assessed using diagnosis, occurrence (Confusion Assessment Method-ICU), and severity scales (Delirium Index).ResultsAll patients presented delirium at entry. The mean oximetry value decreased from 66.4±6.7 (mean±SD) to 50.8±6.8 on the first day after delirium onset and increased in patients whose delirium resorbed over the 3 days. The relationship between oximetry, delirium diagnosis, and severity was analyzed with a marginal model and linear mixed models. Cerebral oximetry was related to delirium diagnosis (P≤.0001) and severity (P≤.0001).ConclusionThis study highlighted the links between increased cerebral oximetry values and delirium resorption. Oximetry values may be useful in monitoring delirium progression, thus assisting in the management of this complicated condition.Copyright © 2016 Elsevier Inc. All rights reserved.

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