• Ir J Med Sci · Jan 2005

    Solitary plasmacytoma: experiences from Central Anatolia.

    • H S Coskun, O Er, S Soyuer, M Altinbas, B Eser, E Karahacioglu, and F Altuntas.
    • Suleyman Demirel University Medical Faculty, Dept. of Internal Medicine, Isparta, Turkey. hscoskun@med.sdu.edu.tr
    • Ir J Med Sci. 2005 Jan 1; 174 (1): 33-6.

    BackgroundSolitary plasmacytoma localised to bone or soft tissue without myeloma.AimClinical features and survival was analysed in patients from Central Anatolia.MethodsTwenty-three solitary plasmacytoma (18 male, 5 female) were evaluated retrospectively. Median age was 58 years (46-72). The major localisation was vertebral column.ResultsAll patients but one (larynx) had surgical resection and 21 patients received radiotherapy postoperatively. Multiple myeloma developed in eight patients (35%) and local relapse was detected in one patient. Eight patients died, causes of death were multiple myeloma progression in six patients, local relapse of intracranial plasmacytoma in one patient and cranial trauma in one patient who was in complete remission. Three and 5 years progression free survival were 45.6% and 22.8% respectively and overall survivals were 54.4% and 27.2% respectively.ConclusionSolitary plasmacytoma cases should be followed carefully regarding local relapse and progression to myeloma.

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