• Clin. Gastroenterol. Hepatol. · Sep 2008

    Case Reports

    Cerebral edema and hyperammonemia after transjugular intrahepatic portosystemic shunt placement in a cirrhotic patient.

    • Robert T Kavitt, Vincent L Yang, and Donald M Jensen.
    • Department of Medicine, Section of Gastroenterology, University of Chicago, Chicago, Illinois 60637, USA.
    • Clin. Gastroenterol. Hepatol. 2008 Sep 1; 6 (9): 1054-6.

    AbstractTransjugular intrahepatic portosystemic shunt (TIPS) placement has been widely performed for nearly two decades and has been shown to alleviate refractory ascites in patients with cirrhosis. Hepatic encephalopathy after TIPS is rarely severe; however, a risk of cerebral edema resulting from hyperammonemia after TIPS does exist. Here we describe a case demonstrating the development of severe hepatic encephalopathy with cerebral edema caused by hyperammonemia as a complication of TIPS in a patient with chronic liver disease with relatively preserved liver function.

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