• J Med Liban · Jul 2007

    Case Reports

    Thyrotoxic periodic paralysis. A case report.

    • Paola Atallah, Elie R Dib, and Mounir Khoury.
    • Department of Endocrinology, Saint George Hospital University Medical Center, Affiliated to the University of Balamand, Faculty of Medicine & Medical Sciences, Division of Endocrinology and Neurology, Beirut, Lebanon. paolaatt@hotmail.com
    • J Med Liban. 2007 Jul 1; 55 (3): 167-9.

    AbstractThyrotoxic hypokalemic periodic paralysis (TPP)--a rare complication of thyrotoxicosis and a medical emergency--is characterized by recurrent episodes of muscle weakness and hypokalemia associated with hyperthyroidism. We report a case of TPP in a 38-year-old white Lebanese male. The patient suffered from severe muscle weakness of the upper and lower limbs. His blood tests revealed hypokalemia (k: 2.4 mEq/L), low thyroid-stimulating hormone TSH (0.001 microIU/mL) and normal levels of thyroid hormones. The thyroid scan showed a hot nodule. His paralysis resolved with IV potassium. The patient was treated with propranolol and radioactive iodine with complete remission of the hyperthyroidism and the paralysis. A discussion of the clinical and pathophysiological features and treatment of TPP is presented.

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