• Annals of plastic surgery · Nov 2009

    Review Case Reports

    The world's experience with facial transplantation: what have we learned thus far?

    • Chad R Gordon, Maria Siemionow, Francis Papay, Landon Pryor, James Gatherwright, Eric Kodish, Carmen Paradis, Kathy Coffman, David Mathes, Stefan Schneeberger, Joseph Losee, Joseph M Serletti, Mikaël Hivelin, Laurent Lantieri, and James E Zins.
    • Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH 44195, USA. gordonc@ccf.org
    • Ann Plast Surg. 2009 Nov 1; 63 (5): 572-8.

    AbstractThe objective of this review article is to summarize the published details and media citations for all seven face transplants performed to date to point out deficiencies in those reports so as to provide the basis for examining where the field of face transplantation stands, and to act as a stimulus to enhance the quality of future reports and functional outcomes. Overall long-term function of facial alloflaps has been reported satisfactorily in all seven cases. Sensory recovery ranges between 3 and 6 months, and acceptable motor recovery ranges between 9 and 12 months. The risks and benefits of facial composite tissue allotransplantation, which involves mandatory lifelong immunosuppression analogous to kidney transplants, should be deliberated by each institution's multidisciplinary face transplant team. Face transplantation has been shown thus far to be a viable option in some patients suffering severe facial deficits which are not amenable to modern-day reconstructive technique.

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