• Nature · Jul 2014

    Review

    Metabolism of stromal and immune cells in health and disease.

    • Bart Ghesquière, Brian W Wong, Anna Kuchnio, and Peter Carmeliet.
    • 1] Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, Department of Oncology, University of Leuven, Leuven B-3000, Belgium [2] Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, VIB, Leuven B-3000, Belgium.
    • Nature. 2014 Jul 10; 511 (7508): 167-76.

    AbstractCancer cells have been at the centre of cell metabolism research, but the metabolism of stromal and immune cells has received less attention. Nonetheless, these cells influence the progression of malignant, inflammatory and metabolic disorders. Here we discuss the metabolic adaptations of stromal and immune cells in health and disease, and highlight how metabolism determines their differentiation and function.

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