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Randomized Controlled Trial Multicenter Study
Early neurologically-focused follow-up after cardiac arrest improves quality of life at one year: A randomised controlled trial.
- Véronique R M Moulaert, Caroline M van Heugten, Bjorn Winkens, Wilbert G M Bakx, Marc C F T M de Krom, Ton P M Gorgels, Derick T Wade, and Jeanine A Verbunt.
- Adelante, Centre of Expertise in Rehabilitation and Audiology, Zandbergsweg 111, 6432 CC Hoensbroek, The Netherlands; CAPHRI School for Public Health and Primary Care, Department of Rehabilitation Medicine, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands. Electronic address: v.moulaert@adelante-zorggroep.nl.
- Int. J. Cardiol. 2015 Aug 15; 193: 8-16.
BackgroundSurvivors of a cardiac arrest frequently have cognitive and emotional problems and their quality of life is at risk. We developed a brief nursing intervention to detect cognitive and emotional problems, provide information and support, promote self-management, and refer them to specialised care if necessary. This study examined its effectiveness.MethodsMulticentre randomised controlled trial with measurements at two weeks, three months and twelve months after cardiac arrest. 185 adult cardiac arrest survivors and 155 caregivers participated. Primary outcome measures were societal participation and quality of life of the survivors at one year. Secondary outcomes were the patient's cognitive functioning, emotional state, extended daily activities and return to work, and the caregiver's well-being. Data were analysed using 'intention to treat' linear mixed model analyses.ResultsAfter one year, patients in the intervention group had a significantly better quality of life on SF-36 domains Role Emotional (estimated mean differences (EMD)=16.38, p=0.006), Mental Health (EMD=6.87, p=0.003) and General Health (EMD=8.07, p=0.010), but there was no significant difference with regard to societal participation. On the secondary outcome measures, survivors scored significantly better on overall emotional state (HADS total, EMD=-3.25, p=0.002) and anxiety (HADS anxiety, EMD=-1.79, p=0.001) at one year. Furthermore, at three months more people were back at work (50% versus 21%, p=0.006). No significant differences were found for caregiver outcomes.ConclusionThe outcomes of cardiac arrest survivors can be improved by an intervention focused on detecting and managing the cognitive and emotional consequences of a cardiac arrest.Trial RegistrationCurrent controlled trials, ISRCTN74835019.Copyright © 2015. Published by Elsevier Ireland Ltd.
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