• Critical care clinics · Jul 2015

    Review

    Sleep Neurobiology and Critical Care Illness.

    • Xavier Drouot and Solene Quentin.
    • CHU de Poitiers, Department of Clinical Neurophysiology, Hôpital Jean Bernard, 2 rue de la Milétrie, Poitiers 86000, France; Univ Poitiers, University of Medicine and Pharmacy, 6 rue de la Milétrie, Poitiers 86000, France; INSERM, CIC 1402, Equipe Alive, CHU de Poitiers, Cours Est J. Bernard, Poitiers 86000, France. Electronic address: xavier.drouot@chu-poitiers.fr.
    • Crit Care Clin. 2015 Jul 1; 31 (3): 379-91.

    AbstractThe intensive care unit (ICU) environment is not propitious for restoring sleep and many studies have reported that critically ill patients have severe sleep disruptions. However, sleep alterations in critically ill patients are specific and differ significantly from those in ambulatory patients. Polysomnographic patterns of normal sleep are frequently lacking in critically ill patients and the neurobiology of sleep is important to consider regarding alternative methods to quantify sleep in the ICU. This article discusses elements of sleep neurobiology affecting the specificity of sleep patterns and sleep alterations in patients admitted to the ICU. Copyright © 2015 Elsevier Inc. All rights reserved.

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