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J. Clin. Microbiol. · Sep 2011
Sensitivity and specificity of immunocytochemical staining of mycobacterial antigens in the cytoplasm of cerebrospinal fluid macrophages for diagnosing tuberculous meningitis.
- Yuquan Shao, Ping Xia, Tao Zhu, Jiong Zhou, Yuan Yuan, Hao Zhang, Jianjun Chen, and Xingyue Hu.
- Department of Neurology, Affiliated Sir Run Run Shaw Hospital, 3 East Qingchun Road, Hangzhou 310016, Zhejiang, China.
- J. Clin. Microbiol. 2011 Sep 1; 49 (9): 3388-91.
AbstractThe sensitivity and specificity of immunocytochemical staining of mycobacterial antigens in the cytoplasm of cerebrospinal fluid (CSF) macrophages for diagnosis of tuberculous meningitis (TBM) was prospectively compared with Ahuja criteria from 393 consecutive CSF specimens. The assay can play an important role for the diagnosis of TBM, with sensitivity of 73.5% and specificity of 90.7%.
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