• Eur J Anaesthesiol · May 2010

    Preoperative chronic pain in radical prostatectomy patients: preliminary evidence for enhanced susceptibility to surgically induced pain.

    • Hans J Gerbershagen, Oguzhan Dagtekin, Jan Gaertner, Frank Petzke, Axel Heidenreich, Rainer Sabatowski, and Enver Ozgür.
    • Department of Anaesthesiology, Division of Perioperative and Emergency Care, University Medical Center Utrecht, Utrecht, The Netherlands. h.j.gerbershagen@umcutrecht.nl
    • Eur J Anaesthesiol. 2010 May 1; 27 (5): 448-54.

    Background And ObjectiveThe aim of the study was to examine a possible relationship between the extent of preoperative chronic pain and the development of moderate-to-severe acute postoperative pain.MethodsEighty-four patients scheduled for radical prostatectomy were studied. Pain intensities after mobilization during the first 3 postoperative days were added to yield a total pain score (total pain score after mobilization, range 0-30). Pain was considered as moderate to severe at a total pain score after mobilization of 12 or higher. The preoperative severity of chronic pain disorders was measured using the Mainz Pain Staging System (I-III). Further possible preoperative risk factors for the development of intense postoperative pain that were examined included pain intensity, pain in the urological site, psychological distress (Hospital Anxiety and Depression Scale) and health-related quality of life (Short Form-12).ResultsPatients with moderate-to-severe preoperative chronic pain and those with higher Mainz Pain Staging System stages were significantly (P < 0.001) more likely to develop moderate-to-severe postoperative pain. Anxiety and depression scores as well as physical health (Short Form-12) were significantly associated with a total pain score after mobilization of at least 12. The development of postoperative pain was independent of the presence of preoperative pain in the urological site.ConclusionThis study demonstrated that higher degrees of preoperative chronic pain were associated with the development of more intense pain after radical prostatectomy. Preoperative psychological distress and reduced physical health were associated with a marked increase in postoperative pain intensity.

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