• Camilo Corbellini, Cristiane Brenner Eilert Trevisan, Jorge Hugo Villafañe, Alexandre Doval da Costa, and Silvia Regina Rios Vieira.
• Postgraduate Program in Medical Sciences, Medical School, Universidade Federal do Rio Grande do Sul, Brazil ; Casa di Cura Villa Serena, Italy.
• J Phys Ther Sci. 2015 Jun 1; 27 (6): 1945-50.

Abstract[Purpose] To evaluate pre-extubation variables and check the discriminative validity of age as well as its correlation with weaning failure in elderly patients. [Subjects and Methods] Two hundred thirty-nine consecutive patients (48% female) who were on mechanical ventilation and had undergone orotracheal intubation were divided into four subgroups according to their age: <59 years, 60-69 years, 70-79 years, and >80 years old. The expiratory volume (VE), respiratory frequency (f), tidal volume (VT), and respiratory frequency/tidal volume ratio (f/VT) were used to examine differences in weaning parameters between the four subgroups, and age was correlated with weaning failure. [Results] The rate of weaning failure was 27.8% in patients aged >80 years and 22.1% in patients aged <60 years old. Elderly patients presented higher f/VT and f values and lower VT values. The areas under the receiver operating characteristic curves for f/VT ratio were smaller than those published previously. [Conclusion] Our results indicate that aging influences weaning criteria without causing an increase in weaning failure.

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