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Randomized Controlled Trial Clinical Trial
Benzydamine for the prevention of pharyngo-laryngeal pathology following tracheal intubation.
- B Mazzarella, A Macarone Palmieri, P Mastronardi, R Spatola, S Lamarca, G De Rosa, and A Mastella.
- Int J Tissue React. 1987 Jan 1; 9 (2): 121-9.
AbstractA clinical study was carried out to assess the antiinflammatory effectiveness and related properties of this drug. It was performed double-blind in 40 adult patients (ASA I, and II) undergoing major otorhinolaryngological surgical procedures with tracheal intubation. The patients received benzydamine at random (n = 20), or a similar solution without the active substance (n = 20). The following parameters were considered: physical examination, sensations referred from patient, cytologic examination, glottographic examination, and spectrographic examination. The results suggest that benzydamine applied locally at a concentration of 0.3% has therapeutic efficacy without local or systemic side-effects.
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