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- V Jiménez-Yuste, A Villar, M Morado, M Canales, M C Hernández, M J Sanjurjo, M Quintana, and F Hernández-Navarro.
- Hemophilia Centre, Department of Hematology, La Paz University Hospital, Madrid, Spain.
- Haemophilia. 2000 Sep 1; 6 (5): 588-90.
AbstractRecombinant activated factor VII (rFVIIa) can be used as an alternative therapy in patients with FVII deficiency. However, as the drug has a very short half-life, continuous infusion could be a meaningful administration modality. We report the case of a 30-year-old woman with moderate FVII deficiency and human immunodeficiency virus infection who underwent a caesarean section delivery. She was treated with a continuous infusion of rFVIIa and did not suffer any bleeding complication. The continuous infusion of rFVIIa was a safe and effective therapeutic approach for our patient, maintaining her levels of FVII:C and avoiding bleeding during caesarean section and afterwards.
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