• M Reggiani and Società Inter-Regionale Piemonte e Valle d'Aosta per le Cerebrovasculopatie Group.
• Clinica Neurologica, Università del Piemonte Orientale A. Avogadro, Novara, Italia.
• Cerebrovasc. Dis. 2009 Jan 1; 27 (1): 29-36.

BackgroundFew studies have addressed predictors of long-term mortality after first-ever ischaemic stroke.MethodsWe prospectively collected data on 361 consecutive patients admitted to 18 neurology departments in Italy for a first-ever ischaemic stroke in 1999, categorized according to the Oxfordshire Community Stroke Project (OCSP) classification. Age, gender, risk factors, previous vascular disease, in-hospital complications, stroke severity, functional status, therapy and living place at admission, discharge and after 6 months were recorded. Follow-up was available for 97% patients at 5 years.ResultsSurvival probability was 91% (95% CI = 88-94) at 1 month, 84% (80-88) at 6 months and 64% (58-69) at 5 years. Mortality was higher for the TACI (total anterior circulation infarct) group compared to the other categories (p < 0.0001). Hazard ratios for 5-year mortality in the final model were: 5.4 for age >or=65 years (p < 0.0001), 2.8 for TACI (p < 0.0001), 2.7 for previous vascular disease (p < 0.01) and 1.9 for cardio-embolic risk according to the TOAST risk stratification (p < 0.05).ConclusionsOur study extends the prognostic value of the OCSP classification to 5-year survival.Copyright 2008 S. Karger AG, Basel.

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