• J Stroke Cerebrovasc Dis · Oct 2013

    Charlson comorbidity index in ischemic stroke and intracerebral hemorrhage as predictor of mortality and functional outcome after 6 months.

    • Pedro Enrique Jiménez Caballero, Fidel López Espuela, Juan Carlos Portilla Cuenca, José María Ramírez Moreno, Juan Diego Pedrera Zamorano, and Ignacio Casado Naranjo.
    • Department of Neurology, San Pedro de Alcántara Hospital, Cáceres, Spain. Electronic address: pjimenez1010j@yahoo.es.
    • J Stroke Cerebrovasc Dis. 2013 Oct 1; 22 (7): e214-8.

    BackgroundThe Charlson Comorbidity Index (CCI) is commonly used in outcome and mortality studies. Our aim was to investigate the association between CCI score and the functional outcome and mortality 6 months after ischemic stroke (IS) or intracerebral hemorrhage.MethodsThis was a prospective observational cohort of patients with spontaneous intracerebral hemorrhage and IS admitted to the stroke unit during 18 months. The modified Rankin scale (mRS) score was obtained for subjects 6 months after event. The CCI score was dichotomized (low comorbidity 0 or 1 versus high ≥ 2) for analysis. The mRS score was also dichotomized (good outcome, mRS score 0 or 1 versus poor outcome, mRS score ≥ 2).ResultsIn all, 175 patients were enrolled in the study. Logistic regression showed that those with a high CCI score (≥ 2) had 37.3% increased odds of having a poor outcome (≥ 2) at 6 months and 68.4% greater odds of death at 6 months.ConclusionsComorbid medical conditions independently influence outcome after IS or intracerebral hemorrhage.Copyright © 2013 National Stroke Association. Published by Elsevier Inc. All rights reserved.

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