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Case Reports
Safety and efficiency of recombinant activated factor VII in postcardiotomy massive hemorrhage.
- Yoan Lamarche, Philippe Demers, Nancy C Poirier, Danielle Robitaille, and Raymond Cartier.
- Department of Surgery, Montreal Heart Institute and Université de Montréal, Montreal, QC, Canada. rc2910@aol.com
- Can J Cardiol. 2007 Aug 1; 23 (10): 809-13.
AbstractPostoperative massive hemorrhage is a difficult clinical situation after cardiac surgery. Recombinant activated factor VII (rf-VIIa) can be a useful adjunct to surgical hemostasis and blood product transfusion. Four cases of massive hemorrhage treated with rf-VIIa after complex cardiac surgery are reported. A review of the literature and possible guidelines for the use of rf-VIIa in cardiac surgery are provided.
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