• Acta neurochirurgica · Jan 1999

    Comparative Study Clinical Trial

    Advantage of intravenous anaesthesia for acute stage surgery of aneurysmal subarachnoid haemorrhage.

    • K Sato, H Karibe, and T Yoshimoto.
    • Department of Neuroanesthesia, Kohnan Hospital, Sendai, Japan.
    • Acta Neurochir (Wien). 1999 Jan 1; 141 (2): 161-3; discussion 163-4.

    AbstractTo investigate the clinical effects of intravenous anaesthesia on surgical procedure and the outcome in acute stage surgery for aneurysmal subarachnoid haemorrhage (SAH), pre-, intra-, and post-operative factors were analyzed to compare between inhalational (IA, n = 38) and intravenous (IVA, n = 37) anaesthesia. IVA significantly shortened the duration of surgery (p < 0.05) and the duration of hospital stay (p < 0.01). These results suggest that IVA may be more suitable than IA for acute stage surgery of aneurysmal SAH. These effects may be mainly caused by IVA's pharmakokinetics, by effects on intracranial homeostasis and metabolism, and neuroprotective properties.

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