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Eur. J. Intern. Med. · Aug 2006
Quantitative acid-base physiology using the Stewart model. Does it improve our understanding of what is really wrong?
- R Derksen, G J Scheffer, and J G van der Hoeven.
- Department of Anesthesiology, University Medical Centre Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands. r.derksen@anes.umcn.nl
- Eur. J. Intern. Med. 2006 Aug 1; 17 (5): 330-3.
AbstractTraditional theories of acid-base balance are based on the Henderson-Hasselbalch equation to calculate proton concentration. The recent revival of quantitative acid-base physiology using the Stewart model has increased our understanding of complicated acid-base disorders, but has also led to several new controversies. With the help of three patient histories, we show that the Henderson-Hasselbalch equation should be regarded as a simplified version of the more general Stewart model and not as something completely different. Therefore, both models may be useful at the bedside.
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