• Cell metabolism · Aug 2014

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    Hormone-sensitive lipase deficiency in humans.

    • Rudolf Zechner and Dominique Langin.
    • Institute of Molecular Biosciences, University of Graz, 8010 Graz, Austria. Electronic address: rudolf.zechner@uni-graz.at.
    • Cell Metab. 2014 Aug 5; 20 (2): 199-201.

    AbstractThe breakdown of cellular fat stores fuels energy production and multiple anabolic processes. Albert et al. (2014) demonstrate that the lack of hormone-sensitive lipase, a member of the enzyme trio that catabolizes fat, has pronounced effects on lipid metabolism, glucose homeostasis, and cell signaling in humans.Copyright © 2014 Elsevier Inc. All rights reserved.

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