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J. Clin. Microbiol. · Jan 2009
Single-nucleotide polymorphisms in Rv2629 are specific for Mycobacterium tuberculosis genotypes Beijing and Ghana but not associated with rifampin resistance.
- Susanne Homolka, Claudio Köser, John Archer, Sabine Rüsch-Gerdes, and Stefan Niemann.
- Forschungszentrum Borstel, National Reference Center for Mycobacteria, Research Center Borstel, Parkallee 1, Borstel, Germany.
- J. Clin. Microbiol. 2009 Jan 1; 47 (1): 223-6.
AbstractSequence analysis of 58 multidrug-resistant Mycobacterium tuberculosis complex strains from Germany and 55 susceptible strains from a reference collection comprising major phylogenetic lineages confirmed that variations in Rv2629, 191A/C and 965C/T, are specific for genotypes Beijing and Ghana, respectively, but not involved in the development of rifampin (rifampicin) resistance.
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