• J. Clin. Microbiol. · Mar 2006

    Sensitive line probe assay that simultaneously detects mutations conveying resistance to lamivudine and adefovir.

    • Munira Hussain, Scott Fung, Evelien Libbrecht, Erwin Sablon, Carmela Cursaro, Pietro Andreone, and Anna S F Lok.
    • Division of Gastroenterology, University of Michigan Medical Center, 1500 East Medical Center Drive, 3912 Taubman Center, Box 0362, Ann Arbor, Michigan 48109-0362, USA.
    • J. Clin. Microbiol. 2006 Mar 1; 44 (3): 1094-7.

    AbstractThe INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the presence of lamivudine and adefovir resistance mutations in clinical samples, has a high degree of concordance with sequencing, and can detect mutants earlier.

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