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Expert Rev Pharmacoecon Outcomes Res · Jun 2013
Vaccination against herpes zoster and postherpetic neuralgia in France: a cost-effectiveness analysis.
- Xavier Bresse, Lieven Annemans, Emmanuelle Préaud, Karine Bloch, Gérard Duru, and Aline Gauthier.
- Sanofi Pasteur MSD, 8 Rue Jonas Salk, 69367 Lyon Cedex 07, France.
- Expert Rev Pharmacoecon Outcomes Res. 2013 Jun 1; 13 (3): 393-406.
AbstractThis study assesses the cost-effectiveness of vaccination against herpes zoster (HZ) and postherpetic neuralgia in France, using a published Markov model. The cost-effectiveness of vaccinating individuals aged from 65 years or between 70 and 79 years was evaluated over their lifetime, from a third-party payer perspective. French-specific data were combined with results from clinical studies and international quality-of-life-based (EuroQol five-dimension questionnaire) utilities from the literature. HZ vaccination was highly cost effective in both populations. Incremental cost-effective ratios were estimated between €9513 and 12,304 per quality-adjusted life year gained, corresponding to €2240-2651 per HZ case avoided and €3539-4395 per postherpetic neuralgia case avoided. In addition to epidemiological and clinical evidence, economic evidence also supports the implementation of HZ vaccination in France.
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