• Ann. Thorac. Surg. · Dec 2012

    Randomized Controlled Trial Multicenter Study Comparative Study

    Sternal closure with rigid plate fixation versus wire closure: a randomized controlled multicenter trial.

    • Jaishankar Raman, Sven Lehmann, Kenton Zehr, Brian J De Guzman, Lishan Aklog, H Edward Garrett, Heber MacMahon, Brian M Hatcher, and Michael S Wong.
    • Department of Cardiothoracic and Vascular Surgery, Rush University Medical Center, Chicago, Illinois 60612, USA. jai_raman@rush.edu
    • Ann. Thorac. Surg. 2012 Dec 1; 94 (6): 1854-61.

    BackgroundRigid bone fixation is the standard of care for all bone reconstructions except that after sternotomy. Sternal reconstruction after median sternotomy using rigid fixation with plates may improve bone healing and reduce pain when compared with wire cerclage.MethodsOne-hundred forty patients at six centers who were determined preoperatively to be at high risk for sternal wound complications were randomly assigned to sternal closure with rigid plate fixation (n=70) or wire cerclage (n=70). Sternal healing was evaluated at 3 or 6 months by a core laboratory using computed tomography. Pain and function were evaluated at postoperative day 3 through discharge, 3 weeks, 6 weeks, 3 months, and 6 months.ResultsSternal healing was superior in rigid plate fixation patients at both 3 and 6 months. Mean computed tomography scores in the rigid plate fixation and wire cerclage groups at 3 months were 1.7±1.1 and 0.9±0.8 (p=0.003). At 6 months, the scores were 3.2±1.6 and 2.2±1.1, respectively (p=0.01). At 6 months, 70% of rigid plate fixation patients had achieved sternal union, compared with 24% of conventional wire cerclage patients (p=0.003). Pain scores and narcotic usage were lower in rigid plate fixation patients. Significant differences in pain scores were observed at 3 weeks for total pain (p=0.020) and pain with coughing (p=0.0084) or sneezing (p=0.030). Complication rates were similar in both groups.ConclusionsSternal reconstruction using rigid fixation with plates improved bone healing and reduced early postoperative pain compared with wire cerclage.Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

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