• Int. J. Infect. Dis. · Sep 2014

    Case Reports

    Acute respiratory failure secondary to eosinophilic pneumonia following influenza vaccination in an elderly man with chronic obstructive pulmonary disease.

    • Prapaporn Pornsuriyasak, Thitiporn Suwatanapongched, Jettanong Klaewsongkram, Supranee Buranapraditkun, and Porpon Rotjanapan.
    • Division of Pulmonary and Critical Care, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi, Bangkok 10400, Thailand. Electronic address: pprapaporn@gmail.com.
    • Int. J. Infect. Dis. 2014 Sep 1; 26: 14-6.

    AbstractAcute respiratory failure with diffuse pulmonary opacities is an unusual manifestation following influenza vaccination. We report herein a patient with chronic obstructive pulmonary disease who developed fever with worsening of respiratory symptoms and severe hypoxemia requiring ventilatory support shortly after influenza vaccination. Bronchoalveolar lavage was compatible with acute eosinophilic pneumonia. Rapid clinical improvement was observed 2 weeks after systemic corticosteroid treatment, followed by radiographic improvement at 4 weeks. No disease recurrence was observed at the 6-month follow-up.Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

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